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Professor Paul Dupree

Abstract:

Xylan and cellulsoe are the most abundant polymers on earth, and provide an emormous reseource for food, deed and renewable materials, including biofuels. Nevertheless, the way the functional material properties arise from the structure and interaction of these polysaccharides is not understood. This project will use plant molecular genetics and biochemistry to manipulate the synthesis and hence structure of xylan. The consequences on material properties will be examined, leading to new hypthotheses of the cell wallstructure: function relationship.

References:

  • Bromley JR, Busse-Wicher M, Tryfona T, Mortimer JC, Zhang Z, Brown D, Dupree P. (2013) GUX1 and GUX2 glucuronyltransferases decorate distinct domains of glucuronoxylan with different substitution patterns. Plant J. 74, 423–34. 
  • Mortimer JC, Miles GP, Brown DM, Zhang Z, Segura MP, Weimar T, Yu X, Seffen KA, Stephens E, Turner SR, Dupree P (2010) Absence of branches from xylan in Arabidopsis gux mutants reveals potential for simplification of lignocellulosic biomass. Proc Natl Acad Sci U S A. 107, 17409-14 
  • Brown DM, Goubet F, Wong VW, Stephens E, Goodacre R, Dupree P, Turner SR (2007) Comparison of five xylan synthesis mutants reveals new insight into the mechanisms of xylan synthesis. Plant Journal 52, 1154-1168

Professor Paul Dupree

Professor Paul Dupree
Department of Biochemistry
Office Phone: 01223 333340