Laura Blenkarn
- PhD Student
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Department of Pharmacology
Research theme: Bioscience for an integrated understanding of health
Research
Project Theme:
Inhibiting Oncogenic Myc through Cyclin T1
Project Summary:
I am utilising PROTAC technology to target Cyclin T1, the regulatory subunit of positive transcription factor b, which regulates both Myc transcription and activity. The purpose of this is twofold: to further understand Cyclin T1's biology and involvement with Myc and to assess Cyclin T1 as a therapeutic target for cancer treatment. This work combines expertise in functional cell line and mouse-model work from the Wilson lab with the drug-design and biophysical testing knowledge of the Itzhaki lab.
Dr Cathy Wilson