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Cambridge Biosciences DTP PhD Programme

 

                    

 

This page includes a list of the research topics in which students (Standard and Targeted) are able to undertake their lab rotations and then standard students will choose their PhD project.

The research topics are grouped into the five BBSRC Research Priorities. You can also search for other potential supervisors on the websites of our participating Departments and Institutes.

 

Bioscience for sustainable agriculture and food
Name: Prof Gerard Bishop
Email: gerard.bishop@niab.com
Department / Partner Institute: NIAB
Website: https://www.niab.com/about/people/professor-gerard-bishop
Research topic for potential rotation projects: Development and analysis and of novel potato periclinal chimeras towards improved stress resilience. Tissue culture techniques will be deployed to generate plant chimeras between wild species and cultivated potato.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Stéphanie Swarbreck
Email: stephanie.swarbreck@niab.com
Department / Partner Institute: NIAB
Website: https://www.niab.com/about/people/dr-stephanie-swarbreck
Research topic for potential rotation projects: Improving root system architecture in cereal crops (e.g. tef or wheat) and their interactions with soil microbial communities can improve their agronomic performance.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof John Carr
Email: jpc1005@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/directory/john-carr
Research topic for potential rotation projects: Most crop-infecting viruses are insect-transmitted. Using engineered Arabidopsis plants and GFP-expressing viruses the student will test strategies to inhibit virus transmission without pesticide use.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Nik Cunniffe
Email: njc1001@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/directory/cunniffe-nik
Research topic for potential rotation projects: Various topics in mathematical modelling of spread, detection, control and/or evolution of plant diseases. Students from all backgrounds are welcome, so long as they know/willing to learn about modelling/simulation.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Julia Davies
Email: jmd32@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/research/groups/transport
Research topic for potential rotation projects: Response to wounding is a key component of the plant's immune response, relying on calcium signalling. We are discovering the receptors and channels involved using imaging combined with protein interactions.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Julian Hibberd
Email: jmh65@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://hibberdlab.com/
Research topic for potential rotation projects: Improving photosynthesis in plants through the discovery of transcription factors that pattern gene expression to specific cells of leaves. A phylogenetically informed analysis will be used.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Johannes Kromdijk
Email: jk417@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/directory/johannes-kromdijk
Research topic for potential rotation projects: 1. Interactive effects of cold and high light on the inhibition of photosynthesis in maize.
2. Engineering of photoprotective energy dissipation in the photosystem II antennae to improve photosynthetic efficiency.
BBSRC DTP secondary strategic theme: Understanding the rules of life, Biosciences for renewable resources and clean growth
Name: Dr Leonie Luginbuehl
Email: lhl28@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/research/groups/plant-physiology-and-symb...
Research topic for potential rotation projects: Exploring the rules of trade in the beneficial symbiosis between plants and arbuscular mycorrhizal fungi using metabolic, transcriptional and genetic approaches.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Beverley Glover
Email: bjg26@cam.ac.uk
Department / Partner Institute: Plant Sciences / Botanic Garden
Website: https://www.plantsci.cam.ac.uk/research/groups/evolution-and-development
Research topic for potential rotation projects: Evolution and development of petal colour, shape and texture - molecular developmental biology and evolution of gene families. Responses of bees to variation in flower morphology and colour, including with crops.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Giles Oldroyd
Email: gedo2@cam.ac.uk
Department / Partner Institute: Plant Sciences / Crop Science Centre
Website: https://www.cropsciencecentre.org/staff/Prof-giles-e-d-oldroyd
Research topic for potential rotation projects: Plants engage with beneficial microorganisms that provide access to limiting nutrients from the environment. My group is attempting to maximise these beneficial associations in crops for sustainable agriculture.
BBSRC DTP secondary strategic theme: Understanding the rules of life, Transformative technologies
Name: Dr Sebastian Schornack
Email: sebastian.schornack@slcu.cam.ac.uk
Department / Partner Institute: Sainsbury Laboratory
Website: http://www.schornacklab.net
Research topic for potential rotation projects: Cell biology, biochemistry and genomics of host-microbe interactions; reprogramming of host development processes by microbial proteins; genome editing; advanced imaging of host-microbe fossils.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Olivier Restif
Email: or226@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.vet.cam.ac.uk/directory/or226@cam.ac.uk
Research topic for potential rotation projects: Analysis of antibiotic resistance gene distribution in pig microbiota and its association with antibiotic use (computer-based project requiring some experience with R or Python).
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof David Aldridge
Email: da113@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/david-aldridge
Research topic for potential rotation projects: 3 exciting projects: i) Microencapsulated, sustainable diets to enhance commercial shellfish quality; ii) Development of mollusc-based bioscaffolds for medicine; iii) Bio-based solutions for wastewater remediation.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Chris Jiggins
Email: c.jiggins@zoo.cam.ac.uk
Department / Partner Institute: Zoology
Website: https://heliconius.zoo.cam.ac.uk/
Research topic for potential rotation projects: We have a variety of projects in insect genomics and evolution. These include plasticity in host plant feeding and toxicity in butterflies, and genetic improvement of the Black Soldier fly for waste bioconversion.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Edgar Turner
Email: ect23@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/dr-edgar-turner
Research topic for potential rotation projects: Using existing datasets, based on long-term experiments in Indonesia, to investigate the impacts of alternative management practices in oil palm to increase the sustainability of palm oil production.
BBSRC DTP secondary strategic theme: n/a
Bioscience for renewable resources and clean growth
Name: Prof Paul Dupree
Email: pd101@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/dupree
Research topic for potential rotation projects: The Dupree plant biochemistry group studies the structure, biosynthesis and function of plant cell walls, with applications in materials, energy and food, using genetics, engineering, microscopy and biochemistry.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Jenny Zhang
Email: jz366@cam.ac.uk
Department / Partner Institute: Chemistry
Website: https://www.ch.cam.ac.uk/group/zhang
Research topic for potential rotation projects: Re-wiring photosynthesis, biohybrid approaches for energy conversion, studying biological 'electromes' using electrochemistry, tackling biofilms and biofouling, many more.
BBSRC DTP secondary strategic theme: Transformative technologies
Understanding the rules of life
Name: Prof Stephen Eglen
Email: sje30@cam.ac.uk
Department / Partner Institute: Applied Mathematics and Theoretical Physics (DAMTP)
Website: https://sje30.github.io
Research topic for potential rotation projects: Computational models of neural development, in particular for understanding the development of ordered connections between eye and brain. Neuroinformatics approaches to understanding neuronal data sets.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Oliver Florey
Email: oliver.florey@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/signalling/oliver-florey/research
Research topic for potential rotation projects: We investigate the molecular mechanisms cells use to maintain a healthy lysosomal network in response to infection and age-associated stresses, using state-of-the art microscopy and biochemical techniques.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Ian McGough
Email: ian.mcgough@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/signalling/ian-mcgough
Research topic for potential rotation projects: The student will determine if oxidative damage of mRNA increases with age to contribute to proteostasis collapse. The amount/identity of oxidised mRNA in young and old Drosophila will be revealed by RNA sequencing.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Teresa Rayon
Email: teresa.rayon@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://rayonlab.org/
Research topic for potential rotation projects: Studying the regulatory and dynamic processes that control timing in development with mouse and human embryonic stem cells and embryos. We employ a variety of quantitative and omic techniques.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Peter Rugg-Gunn
Email: peter.rugg-gunn@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/epigenetics/peter-rugg-gunn
Research topic for potential rotation projects: We are fascinated by the topic of human developmental epigenetics. We study early-stage human embryos and embryo-like models to understand the dynamics of epigenome programming and developmental gene regulation.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Hayley Sharpe
Email: hayley.sharpe@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/signalling/hayley-sharpe
Research topic for potential rotation projects: We aim to understand principles of cell-cell communication. Our latest research focuses on mechanoregulation of phosphotyrosine signalling through the interplay of kinases and phosphatases.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Sophie Trefely
Email: Sophie.Trefely@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/epigenetics/sophie-trefely
Research topic for potential rotation projects: How do nutrients affect cell identity? We develop and apply metabolomics strategies to uncover new metabolic pathways affecting the nucleus and study their role in epigenetic programming.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Martin Turner
Email: martin.turner@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/immunology/martin-turner
Research topic for potential rotation projects: use primary lymphocytes and genetic modification as a system to study inducible gene regulation. Project will teach molecular biology, cell culture, Cas9 ribonucleoprotein transfection and computational skills .
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Philipp Voigt
Email: philipp.voigt@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/epigenetics/philipp-voigt
Research topic for potential rotation projects: We aim to determine how histone acetyltransferases and chromatin remodellers regulate the establishment and functional readout of poised chromatin states in embryonic stem cells and during differentiation.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Alex Borodavka
Email: ab2677@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.borodavkalab.org/
Research topic for potential rotation projects: Biophysics of viral replicative biomolecular condensates; chaperone-assisted RNA folding and RNA interactomes of multi-segmented viral genomes; exploring dsRNA viruses as novel therapeutics and vaccine candidates.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food, Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Marc de la Roche
Email: mad58@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/delaroche
Research topic for potential rotation projects: Developing immune therapies using cancer organoids.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Florian Hollfelder
Email: fh111@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://hollfelder.bioc.cam.ac.uk/
Research topic for potential rotation projects: Investigating cell biological and chemical mechanisms with new ultrahigh-throughput technologies - Protein engineering, discovery and evolution; Single cell transcriptomics for developmental biology.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Kathryn Lilley
Email: ksl23@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/lilley
Research topic for potential rotation projects: SUMO modification plays a major role the plant response to abiotic and biotic stress. Here, you will use chemical labelling and proteomics to study the stress-related regulation of SUMO modification via oxidation.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Ben Luisi
Email: bfl20@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/luisi
Research topic for potential rotation projects: Structural and mechanism of multi-drug efflux machines.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Eyal Maori
Email: em514@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/maori
Research topic for potential rotation projects: RNA communication between honeybees and their microbiome. This project will provide insights that could potentially be translated into RNA solutions to enhance sustainable agriculture, health and disease control.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Juan Mata
Email: jm593@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/mata
Research topic for potential rotation projects: We study how cells respond to stress by modulating translation, using the fission yeast S. pombe. Rotation projects will investigate how cells regulate translation by stalling ribosomes on specific codons.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Daniel Nietlispach
Email: dn206@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/nietlispach
Research topic for potential rotation projects: G protein-coupled receptors are key to regulation of human physiology. We are investigating the molecular mechanism of GPCR activation and the role of receptor plasticity and dynamics in cellular communication.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Luca Pellegrini
Email: lp212@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/pellegrini
Research topic for potential rotation projects: Molecular mechanisms of DNA replication and repair, relevant to genomic stability and cancer. Relevant experimental techniques are Structural Biology (cryoEM) and Biophysics (study of macromolecular interactions).
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Jussi Taipale
Email: ajt208@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.taipalelabs.org/
Research topic for potential rotation projects: When and where genes are expressed.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Ross Waller
Email: rfw26@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: http://www.wallercellevolution.com
Research topic for potential rotation projects: Pathogenic symbioses of apicomplexan parasites: using systems biology and experimental cell biology, all within an evolutionary framework, we ask how these single-celled parasites outwit their human and animal hosts.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr David Gershlick
Email: dg553@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR)
Website: https://www.gershlicklab.com/
Research topic for potential rotation projects: We are interested in the fundamental rules underlying membrane trafficking. We have a particular interest in understanding protein secretion and what goes wrong in the case of neurodegenerative disorders.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Janin Lautenschlager
Email: jl865@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR)
Website: https://www.lautenschlager-lab.com/
Research topic for potential rotation projects: We study biomolecular condensates at the synapse in health and disease using protein droplet, cell biology assays, and super-resolution imaging on the unique lamprey giant synapse.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Jonathon Nixon-Abell
Email: jjn36@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR)
Website: https://www.cimr.cam.ac.uk/staff/dr-jonathon-nixon-abell
Research topic for potential rotation projects: Our work combines advanced microscopy with biophysical and multi-omics approaches to understand mechanisms of organellar communication in neurons and how these processes are corrupted in neurodegenerative disease.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Jeanne Salje
Email: jss53@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR) / Pathology / Biochemistry
Website: https://www.cimr.cam.ac.uk/staff/dr-jeanne-salje
Research topic for potential rotation projects: The Salje lab studies the fundamental biology of obligate intracellular bacteria using a range of approaches including cell biology, transcriptomics/proteomics, and microscopy.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Benjamin Nicholson
Email: ben.nicholson@cruk.cam.ac.uk
Department / Partner Institute: Cancer Research UK Cambridge Institute
Website: http://www.hannonlab.org/team/
Research topic for potential rotation projects: My team studies a range of areas, including transcription, export, and processing of small RNAs, as well as the establishment and maintenance of chromatin marks required for transposon silencing.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Sebastian Ahnert
Email: sea31@cam.ac.uk
Department / Partner Institute: Chemical Engineering and Biotechnology
Website: http://www.tcm.phy.cam.ac.uk/~sea31/
Research topic for potential rotation projects: Genotype-phenotype (GP) maps, both from a general point of view, and in terms of the impact of the GP map on evolution, and the robustness, evolvability, modularity, and complexity of structural phenotypes.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Gabriel Balmus
Email: gb318@cam.ac.uk
Department / Partner Institute: Clinical Neurosciences
Website: https://www.balmuslab.org/
Research topic for potential rotation projects: Role of DNA damage in neurodegenerative disease (Huntingtons or ALS) and ageing by using CRISPR CAS9 genetics.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Thomas Keane
Email: tk2@ebi.ac.uk
Department / Partner Institute: EMBL's European Bioinformatics Institute (EMBL-EBI)
Website: https://www.ebi.ac.uk/people/person/thomas-keane/
Research topic for potential rotation projects: The Keane laboratory uses rodent species models to study the genetic mechanisms of human disease. Projects include genomic structure, regulation, and origins of the most diverse regions of the mouse genome.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Somenath Bakshi
Email: sb2330@cam.ac.uk
Department / Partner Institute: Engineering
Website: https://www.bakshilab.net/
Research topic for potential rotation projects: Single-cell analysis of the effects of antimicrobials and bacteriophages on bacteria to understand: 1. Emergence of antimicrobial resistance (AMR), 2. Phage-bacteria co-evolution, and 3. Phage therapy to combat AMR.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Timothy O'Leary
Email: tso24@cam.ac.uk
Department / Partner Institute: Engineering
Website: http://www.eng.cam.ac.uk/profiles/tso24
Research topic for potential rotation projects: 1. Data driven modelling of environmental perturbations on nervous systems in marine species.
2. Analysis of neural representations of behaviour and/or BMI data.
3. Bio-inspired neuromorphic computation.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Erik Clark
Email: ec491@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/research/research-groups/clark-group
Research topic for potential rotation projects: Gene regulatory networks and patterning dynamics in the early Drosophila embryo; robustness and evolvability of developmental patterning systems.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Richard Durbin
Email: rd109@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/directory/richard-durbin
Research topic for potential rotation projects: Advances in DNA sequencing technology are enabling a new era of genome sequencing across the tree of life. Projects are available in comparative evolutionary sequence analysis, e.g. of genes, diversity, centromeres.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Carol Edwards
Email: cae28@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/research-groups/research-groups/ferguson-smith. I am a Senior Research Associate and Deputy PI in the Lab of Anne Ferguson-Smith.
Research topic for potential rotation projects: Genomic imprinting as a model for dissecting the role of regulatory hierarchies in governing regional control of the mammalian genome.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Michael Imbeault
Email: mi339@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/research-groups/research-groups/imbeault
Research topic for potential rotation projects: KRAB zinc fingers silence mobile elements and participate in the evolution of gene regulation. We have projects related to primate-specific aspects of pancreas development, inflammation, or the DNA damage response.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Cahir O'Kane
Email: cjo1003@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/research-groups/research-groups/okane
Research topic for potential rotation projects: Axon ER is continuous over great distances, potentially allowing long-distance communication. Mutations that remodel it cause axon degeneration. We use imaging and EM in Drosophila and primates to study its roles.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Aylwyn Scally
Email: aos21@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/research-groups/research-groups/scally
Research topic for potential rotation projects: Investigating the ancestry and demography of past populations using computational methods and whole genome sequences from ancient and historical individuals.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Marisa Segal
Email: ms433@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/directory/marisa-segal
Research topic for potential rotation projects: A synthetic approach for exploring Ras oncoprotein inhibition by a novel class of Ras-interacting proteins.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Ben Steventon
Email: bjs57@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://steventonlab.wordpress.com/
Research topic for potential rotation projects: Exploring the interplay of morphogenesis and pattern formation in the self-organisation of the embryonic body plan using explants of the early zebrafish embryo.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Felipe Karam Teixeira
Email: fk319@cam.ac.uk
Department / Partner Institute: Genetics / Physiology, Development and Neuroscience (PDN)
Website: https://karamteixeira.wixsite.com/website
Research topic for potential rotation projects: Molecular mechanisms controlling germline stem cell biology in vivo and protecting the germline genome.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Iva Tchasovnikarova
Email: it257@cam.ac.uk
Department / Partner Institute: Gurdon Institute
Website: https://www.tchasovnikarova-lab.org
Research topic for potential rotation projects: Fluorogenetic interrogation of chromatin pathways: we use genetic screening technologies to dissect the mechanisms underlying epigenetic repression to understand how they are corrupted in diseases such as cancer.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Fengzhu Xiong
Email: fx220@cam.ac.uk
Department / Partner Institute: Gurdon Institute
Website: https://www.gurdon.cam.ac.uk/people/fengzhu-xiong/
Research topic for potential rotation projects: What forces drive tissue morphogenesis? How do embryos regulate tissue mechanics to develop in a robust and coordinated manner? We offer a variety of projects at the biology-physics interface within a diverse team.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Julie Ahringer
Email: ja219@cam.ac.uk
Department / Partner Institute: Gurdon Institute / Genetics
Website: https://www.gurdon.cam.ac.uk/people/julie-ahringer/
Research topic for potential rotation projects: Our research spans two areas: (1) Using single-cell profiling to understand how the genome directs development, (2) Functional analysis of constitutive heterochromatin, both through analyses in C. elegans.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Daniel St Johnston
Email: ds139@cam.ac.uk
Department / Partner Institute: Gurdon Institute / Genetics
Website: http://www2.gurdon.cam.ac.uk/~stjohnstonlab/research.html
Research topic for potential rotation projects: Possible projects:
1) Testing if polarity proteins cluster by phase separation with super-resolution microscopy
2) Analysing the role of polarity proteins in mammalian organoids
3) How does aPKC regulate Crumbs?
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Elisa Laurenti
Email: el422@cam.ac.uk
Department / Partner Institute: Haematology / MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/laurenti
Research topic for potential rotation projects: Molecular regulation of human haematopoietic stem cell function across a human lifetime.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Maria Adelaida Duque Correa
Email: mad75@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/duque-correa
Research topic for potential rotation projects: Investigating the impact of helminth (whipworm and hookworm) infection on the damage and regeneration of the intestinal and alveolar stem cell niche.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Brian Hendrich
Email: bdh24@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/hendrich
Research topic for potential rotation projects: How chromatin remodellers facilitate transduction of extracellular signalling through enhancers to drive transcriptional change in pluripotent cells during cell fate decisions.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Mekayla Storer
Email: ms2786@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/storer
Research topic for potential rotation projects: We are focused on identifying the mechanisms that determine whether injury stimulates endogenous regeneration or fibrotic scar formation, using the mammalian digit tip as a model system.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Giles Yeo
Email: gshy2@cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS)
Website: https://www.mrl.ims.cam.ac.uk/research/principal-investigators/giles-yeo/
Research topic for potential rotation projects: We study pathways that play a role in the brain control of appetite & bodyweight, using single cell & spatial transcriptomic approaches to map the human hypothalamus & hindbrain across the weight spectrum.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Fiona Gribble
Email: fmg23@cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.mrl.ims.cam.ac.uk/research/principal-investigators/fiona-gri...
Research topic for potential rotation projects: Either a) intestinal organoids to investigate signalling involved in secretion of gut hormones controlling body weight; b) mass spectrometry peptidomics to identify and quantify low abundance peptides and proteins.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Jelle van den Ameele
Email: jv361@cam.ac.uk
Department / Partner Institute: MRC Mitochondrial Biology Unit (MBU) / Clinical Neurosciences
Website: https://www.mrc-mbu.cam.ac.uk/research-groups/van-den-ameele-group
Research topic for potential rotation projects: Epigenetic modifications rely on small metabolites, acting as a direct sensor for cellular metabolism. We develop tools to study regulation of chromatin metabolism in Drosophila and mouse neural stem cells in vivo.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr L. Miguel Martins
Email: lm795@cam.ac.uk
Department / Partner Institute: MRC Toxicology Unit
Website: https://www.mrc-tox.cam.ac.uk/staff/l-miguel-martins
Research topic for potential rotation projects: We aims to identify the molecular initiating events and downstream toxicity pathways, associated with mitochondrial damage: https://www.mrc-tox.cam.ac.uk/research/research-group
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Vito Mennella
Email: vm430@cam.ac.uk
Department / Partner Institute: MRC Toxicology Unit
Website: https://www.mrc-tox.cam.ac.uk/research/research-groups/mennella-group
Research topic for potential rotation projects: Functional analysis of novel GPCR targets expressed in airway motile cilia by CRISPR Cas9, super-resolution imaging and activation assays.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Betty Chung
Email: bcy23@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/betty-chung
Research topic for potential rotation projects: Rapid regulation of protein synthesis and translational control during host pathogen interaction or in response to environmental changes.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Pier Paolo D'Avino
Email: ppd21@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/research/cellular-and-molecular-pathology-div...
Research topic for potential rotation projects: We study the mechanisms that govern cell division in eukaryotic cells and their de-regulation in cancer cells, and in particular how the dynamics and functions of mitotic proteins are regulated by phosphorylation.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Andrew Firth
Email: aef24@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/andrew-firth
Research topic for potential rotation projects: Topics include RNA virus gene expression, comparative genomics and molecular biology, non-canonical translation mechanisms, novel virus discovery, ribosome profiling, RNA structure and function, and bioinformatics.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Camilla Godlee
Email: cbjg2@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://orcid.org/0000-0001-5520-3233
Research topic for potential rotation projects: Studying how Chalmydia virulence proteins interact with the membrane systems of infected eukaryotic cells using microscopy and other cell biological and biochemical techniques. In collaboration with Richard Hayward.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Julia Kenyon
Email: jck33@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/dr-julia-kenyon
Research topic for potential rotation projects: We look at how RNAs are structured and how those structures control the functions of the RNA. We do this for viral RNAs (including HIV, FIV, and flaviviruses like dengue) as well as cancer-related RNAs.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Adrian Liston
Email: al989@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/research/immunology-division/liston-dooley-group
Research topic for potential rotation projects: A new type of white blood cell with potential to regulate the strength of vaccine responses: the Foxp3+ CD8 regulatory T cells.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Naomi McGovern
Email: nm390@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/naomi-mcgovern
Research topic for potential rotation projects: We study mononuclear phagocytes (dendritic cells and macrophages) in the context of infection and autoimmunity. We use technologies including single cell RNA sequencing, flow cytometery and confocal microscopy.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Catherine Merrick
Email: cjm48@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/catherine-merrick
Research topic for potential rotation projects: Basic biology of human malaria parasites. Aspects of DNA biology including replication & the unusual Plasmodium cell cycle, epigenetic control of virulence pathways, unusual DNA/RNA structures called G-quadruplexes.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Laura Itzhaki
Email: lsi10@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/Itzhaki/research
Research topic for potential rotation projects: Engineering proteins with novel functions for therapeutic purposes (e.g. to drive the degradation of disease-associated targets; self-assembling proteins as genetically encoded phase-separating bioreactors).
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Dr Janet Kumita
Email: jrk38@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/kumita
Research topic for potential rotation projects: Understanding the molecular mechanisms of protein self-assembly processes in order to identify novel methods to be used as therapeutic strategies for neurodegenerative diseases.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Paul Miller
Email: pm676@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/miller
Research topic for potential rotation projects: Structural and Pharmacological characterisation of antibody and/or peptide toxin modulators of neuronal ion channels.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health, Transformative technologies
Name: Prof Ewan Smith
Email: es336@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/Smith
Research topic for potential rotation projects: The naked mole-rat is an exceptionally long lived mammal, but the reasons for this remain to be discovered. We use a variety of techniques to further understanding of healthy ageing in this species.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Pietro Cicuta
Email: pc245@cam.ac.uk
Department / Partner Institute: Physics
Website: https://people.bss.phy.cam.ac.uk/~pc245/
Research topic for potential rotation projects: I work on three areas: ciliated epithelia; blood stage malaria parasites; bacteria physiology and infection. For a short rotation project bacteria (high throughput single cell imaging) is best.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Diana Fusco
Email: df390@cam.ac.uk
Department / Partner Institute: Physics
Website: https://dianafusco.wixsite.com/fuscolab
Research topic for potential rotation projects: 1. The evolution of phenotypic plasticity in Bacillus subtilis biofilms.
2. Phage-bacteria coevolution in complex environments.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Clare Baker
Email: cvhb1@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/clare-baker
Research topic for potential rotation projects: Studying the development of electroreceptors in teleost fishes that independently evolved lateral line electroreception (catfish, knifefish): insights into vertebrate sensory cell-type development and evolution.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Riccardo Beltramo
Email: ric.beltramo@gmail.com
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.beltramolab.org/
Research topic for potential rotation projects: We combine electrophysiology, imaging and optogenetics to study the interactions between the visual and spatial navigation systems, in ethologically relevant behaviours and in mouse models of stress-induced anxiety.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Clare Buckley
Email: ceb85@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/clare-buckley
Research topic for potential rotation projects: My group uses optogenetic approaches within the developing zebrafish neural tube and mESC cultures to uncover how mechanics and biochemical signalling work together to shape epithelial organs during development.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Angeleen Fleming
Email: af425@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/angeleen-fleming
Research topic for potential rotation projects: This project will investigate the role of autophagy in maintaining neuronal homeostasis in vivo, using transgenic zebrafish where we can up- and down-regulate autophagy in discrete cell types e.g., neurons and glia.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Elisa Galliano
Email: eg542@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://gallianolab.org/
Research topic for potential rotation projects: We study neuronal plasticity and its links to behaviour in the mouse olfactory system, using ephys/imaging/operant conditioning. We also focus on olfactory bulb dopaminergic neurons and adult neurogenesis.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Courtney Hanna
Email: cwh36@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/staff/hanna
Research topic for potential rotation projects: Investigating the role for epigenetic programming in placental development, using mouse genetics, embryology, imaging, multi-omics, and single-cell sequencing approaches.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Allan Herbison
Email: aeh36@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/allan-herbison
Research topic for potential rotation projects: Learn and use acute brain slice GCaMP imaging in genetic mouse models to determine the effects of serotonin on the burst firing and synchronized activity of hypothalamic neural networks.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Sepiedeh Keshavarzi
Email: sk2244@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.keshavarzilab.com/
Research topic for potential rotation projects: We investigate the neural circuits underlying self-motion and spatial orientation. Our goal is to understand how various sensory signals drive these computations and their impact on perception and behaviour.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Julija Krupic
Email: jk727@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.krupiclab.com/
Research topic for potential rotation projects: Our aim is to understand how space is represented in the hippocampus/mEC and how these representations support memory and goal-directed navigation. We use modelling, electrophys and two photon imaging in rodents.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Kathy Niakan
Email: kkn21@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.trophoblast.cam.ac.uk/people/Prof-kathy-niakan
Research topic for potential rotation projects:
The research project will develop and utilise genetic perturbation, advanced imaging and single-cell multi-omics methods to dissect the function of genes during human embryogenesis.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Ewa Paluch
Email: ekp25@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://paluchlab.uk
Research topic for potential rotation projects: Biology and mechanics of morphogenesis in development, physiology and disease.
We study the cross-talk between molecular processes, cell shape, and cell fate in cultured cells, organoids and in vivo models.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Ole Paulsen
Email: op210@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/ole-paulsen
Research topic for potential rotation projects: We offer rotation projects in three areas of research:
(1) synaptic plasticity underlying hippocampal memory.
(2) mechanism of cortical network oscillations.
(3) cerebral organoid disease models .
Visit our web site!
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Jasper Poort
Email: jp816@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/svl
Research topic for potential rotation projects: The computational mechanisms of learning, attention, and decision-making in the visual cortex of healthy mice and mouse models of neurodevelopmental disorders.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Alberto Rosello-Diez
Email: ar2204@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.rosellodiezlab.com/
Research topic for potential rotation projects: Molecular and cellular mechanisms involved in building organs of the right size and proportions: We use mouse genetic injury models and rat-to-mouse chimeras to reveal how the fetal limb adapts to growth challenges.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Benedicte Sanson
Email: bs251@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/benedicte-sanson
Research topic for potential rotation projects: Tricellular junctions are important during epithelial morphogenesis but mechanisms are elusive. The project will focus on the IgSF adhesion molecule Sidekick, a key component of tricellular adherens junctions.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Milka Sarris
Email: ms543@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/milka-sarris
Research topic for potential rotation projects: We study leukocyte motion and communication within tissues. Projects are available to investigate hitherto uncharted migratory journeys of inflammatory cells after infection and the functional implications.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Elena Scarpa
Email: es697@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/staff/scarpa
Research topic for potential rotation projects: Cells migrating in vivo have to squeeze through small spaces. We use neural crest cells of the Zebrafish as model to understand the consequences of mechanical compressive stresses on cell migration and mitosis.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Keita Tamura
Email: kt532@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/staff/tamura
Research topic for potential rotation projects: Perception and memory strongly influence each other. We aim to decompose those entangled processes of visual cognition into defined neuronal circuits through cutting-edge opto-physiological approaches.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Sumru Bayin
Email: nsb44@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN) / Gurdon Institute
Website: https://www.bayinlab.com
Research topic for potential rotation projects: Age-dependent regenerative mechanisms in the brain.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Eleanor Raffan
Email: er311@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN) / MRC Institute of Metabolic Science (IMS)
Website: https://www.pdn.cam.ac.uk/directory/eleanor-raffan
Research topic for potential rotation projects: Lessons from dogs on obesity genetics and interspecies communication: To find obesity genes we start with dog GWAS and perform comparative studies in humans followed up with molecular biology and physiology experiments to understand mechanisms. A new research programme will use EEG to study interspecies communication between dogs and humans.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Jake Harris
Email: cjh92@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/research/groups/chromatin-memory
Research topic for potential rotation projects: Investigating the role of chromatin in priming plants for enhanced resilience using genomics, molecular biology and CRISPR-based epigenome engineering.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Ian Henderson
Email: irh25@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/directory/ian-henderson
Research topic for potential rotation projects: Using nanopore long-read sequencing to assemble and understand the genetic and epigenetic organisation of centromeres in plant genomes. The project will also use CRISPR/Cas9 to remodel the centromeric repeat arrays.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Alex Webb
Email: aarw2@cam.ac.uk
Department / Partner Institute: Plant Sciences
Website: https://www.plantsci.cam.ac.uk/research/groups/circadian-signal-transduc...
Research topic for potential rotation projects: Circadian clocks in wheat and Arabidopsis.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Samuel Brockington
Email: sb771@cam.ac.uk
Department / Partner Institute: Plant Sciences / Botanic Garden
Website: https://www.plantsci.cam.ac.uk/research/groups/evolution-and-diversity
Research topic for potential rotation projects: We explore how and why life has evolved colour, and in this context, you will help unravel the molecular evolution of a novel colour system, called betalains, which have exceptional value for health and nutrition.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Lida Derevnina
Email: ld645@cam.ac.uk
Department / Partner Institute: Plant Sciences / Crop Science Centre
Website: https://www.plantsci.cam.ac.uk/research/groups/crop-pathogen-immunity
Research topic for potential rotation projects: Deciphering the molecular mechanisms that underpin NLR-mediated suppression.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Uta Paszkowski
Email: up220@cam.ac.uk
Department / Partner Institute: Plant Sciences / Crop Science Centre
Website: https://www.cropsciencecentre.org/staff/Prof-uta-paszkowski
Research topic for potential rotation projects: My lab found that the rice Arbuscular Receptor-like Kinase ARK1 is required for sustenance of the arbuscular mycorrhizal symbiosis. Here, we wish to functionally characterise additional signalling components.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Duncan Astle
Email: duncan.astle@mrc-cbu.cam.ac.uk
Department / Partner Institute: Psychiatry / MRC Cognition and Brain Sciences Unit (CBU)
Website: https://www.astlelab.com/
Research topic for potential rotation projects: We are interested in the developing brain, and we use artificial models to simulate how complex networks form and produce diverse outcomes, including in children with neurodevelopmental conditions.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Jeff Dalley
Email: jwd20@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.neuroscience.cam.ac.uk/directory/profile.php?jwd20
Research topic for potential rotation projects: Understanding the neurobiological determinants of individual differences in behaviour and cognition using high-resolution magnetic resonance imaging, transcriptomics, and other state-of-the-art technologies.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Zoe Kourtzi
Email: zk240@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.abg.psychol.cam.ac.uk
Research topic for potential rotation projects: Multimodal imaging and computational modelling for brain plasticity in health and disease (eg ageing, neurodegenerative disorders).
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Sarah Lloyd-Fox
Email: sl868@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.psychol.cam.ac.uk/people/dr-sarah-lloyd-fox
Research topic for potential rotation projects: Advances in wearable NIRS technology enable imaging brain function in any environment, making it accessible to a wide range of populations incl. global health and preterm infant human brain function studies.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Francois Nedelec
Email: fjn28@cam.ac.uk
Department / Partner Institute: Sainsbury Laboratory
Website: https://www.slcu.cam.ac.uk/research/nedelec-group
Research topic for potential rotation projects: At the interface between physics and biology, we use modelling to study how dynamic structures of the cytoskeleton form and evolve such as to drive essential cellular events such as division, morphology, polarity.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Katharina Schiessl
Email: ks846@cam.ac.uk
Department / Partner Institute: Sainsbury Laboratory
Website: https://www.slcu.cam.ac.uk/people/katharina-schiessl
Research topic for potential rotation projects: Uncover how beneficial nitrogen-fixing bacteria and parasitic root-knot nematodes can exploit plant organ development to induce parasitic root galls and symbiotic nodules using molecular genetics and imaging tools.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Renske Vroomans
Email: renske.vroomans@slcu.cam.ac.uk
Department / Partner Institute: Sainsbury Laboratory
Website: https://www.slcu.cam.ac.uk/staff/renske-vroomans
Research topic for potential rotation projects: We build computational models to study how the developmental mechanisms evolve that generate plant form and function. An example project is the evolution of flower patterns, in collaboration with the Moyroud group.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Edwige Moyroud
Email: em500@cam.ac.uk
Department / Partner Institute: Sainsbury Laboratory / Genetics
Website: https://www.slcu.cam.ac.uk/people/edwige-moyroud
Research topic for potential rotation projects: The project will use new experimental and computational tools, genetics and biochemistry approaches and various imaging techniques to examine the evo-devo mechanisms that specify diverse trichomes types in Hibiscus.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Mark Blaxter
Email: mb35@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: https://www.sanger.ac.uk/person/blaxter-mark/
Research topic for potential rotation projects: Junk or treasure? Horizontal transfer of DNA into animal genomes.
Genomes experience a slow rain of insertions - from transposons, organelles and other species. What are the origins and fates of transferred DNAs?
BBSRC DTP secondary strategic theme: n/a
Name: Dr Trevor Lawley
Email: tl2@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: http://www.lawleylab.com
Research topic for potential rotation projects: Co-evolution of bacteria to breastmilk metabolism using large scale genome datasets from bacteria cultured and purified from infants around the globe. The student will learn computational methods to study bacteria.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Leopold Parts
Email: leopold.parts@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: https://www.sanger.ac.uk/person/parts-leopold/
Research topic for potential rotation projects: Measuring, characterizing, probabilistic modeling, and machine learning human DNA mutation effects at large scale using biochemical and cellular assays with sequencing readouts.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Roser Vento-Tormo
Email: rv4@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: https://ventolab.org/
Research topic for potential rotation projects: During the rotation, the student will perturb organoids with gene editing tools and synthetic drugs to mechanistically dissect biological process.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Julian Parkhill
Email: jp369@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.vet.cam.ac.uk/staff/Prof-julian-parkhill-frs-fmedsci
Research topic for potential rotation projects: We study bacterial evolution, mainly using genomics; the emergence of bacterial lineages, transmission within and between human and animals, and adaptation to the host, and antibiotic pressure.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Walter Federle
Email: wf222@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/research/groups/insect-biomechanics
Research topic for potential rotation projects: How do animals and plants cope with physical constraints? Rotation projects are in 3 main areas: a)Bio-adhesion and functional surfaces, b)Insect biomechanics and locomotion, c)Biomechanics of insect-plant interactions.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Iris Hardege
Email: ih287@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/dr-iris-hardege
Research topic for potential rotation projects: We are interested in how nervous systems generate behaviour by studying the surprising complexity of neurotransmitter receptors in C. elegans, using electrophysiology, behavioural analysis, and molecular biology.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Rebecca Kilner
Email: rmk1002@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/rebecca-kilner
Research topic for potential rotation projects: Burying beetles care for their larvae. Males and females take on different duties, causing males to have larger heads than females. But when does this dimorphism develop? And is it sensitive to diet or competition?
BBSRC DTP secondary strategic theme: n/a
Name: Dr Torsten Krude
Email: tk218@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/research/cell-and-developmental-biology/neural...
Research topic for potential rotation projects: Epigenetic marking of human DNA replication origins - focussing on biogenesis, biochemical nature and functional significance of DNA modifications for the specification of DNA replication origins genome-wide.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Matthias Landgraf
Email: ml10006@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/dr-torsten-krude
Research topic for potential rotation projects: We investigate a 'critical' developmental period when nerve cells set their functional properties, via metabolic signals and epigenetic changes. We study this through imaging, genetics, ‘omics, e-phys and behaviour.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Adria LeBoeuf
Email: acl79@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://leboeuflab.com
Research topic for potential rotation projects: Many animals share materials socially (e.g. milk, regurgitate, ejaculate) that allow one individual's genome to influence another's physiology & fitness. Keywords: ants, multi-omics, behaviour, metabolism, aging.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Emília Santos
Email: es754@cam.ac.uk
Department / Partner Institute: Zoology
Website: https://www.zoo.cam.ac.uk/directory/emilia-santos
Research topic for potential rotation projects: Evolutionary and developmental biology, Functional genomics, Gene regulation, Pigmentation development, Neural Crest Cell Development.
Model system: several species of cichlid fishes.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Tim Weil
Email: tw419@cam.ac.uk
Department / Partner Institute: Zoology
Website: http://www.weillabcambridge.com
Research topic for potential rotation projects: We aim to understand how a single cell becomes a fully functioning organism. We want to understand the mechanisms that coordinate egg development; with a particular interest in the role of biomolecular condensates.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Daniel Field
Email: djf70@cam.ac.uk
Department / Partner Institute: Zoology / Earth Sciences
Website: http://www.fieldpalaeo.com
Research topic for potential rotation projects: We study three-dimensional vertebrate morphology using CT scans. We focus on comparative anatomy of birds and their extinct fossil relatives. The student will work on visualising avian modern and fossil morphology.
BBSRC DTP secondary strategic theme: n/a
Transformative technologies
Name: Prof Mike Weekes
Email: mpw1001@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR)
Website: https://www.cimr.cam.ac.uk/staff/professor-michael-weekes
Research topic for potential rotation projects: We will characterise the function of 10 key human cytomegalovirus genes via CRISPR-based gene knockout then multiplexed proteomic analysis of infected cells. This will reveal novel viral immune evasion strategies.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Susanne Bornelöv
Email: susanne.bornelov@cruk.cam.ac.uk
Department / Partner Institute: Cancer Research UK Cambridge Institute
Website: http://www.sblab.uk/
Research topic for potential rotation projects: We use bioinformatic and artificial intelligence (AI) methods to model gene regulatory processes in order to decipher the role of codon usage and other sequence features in protein synthesis and mRNA stability.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Clemens Kaminski
Email: cfk23@cam.ac.uk
Department / Partner Institute: Chemical Engineering and Biotechnology
Website: https://laser.ceb.cam.ac.uk/
Research topic for potential rotation projects: Development and application of optical superresolution microscopy techniques for the study of biological systems living in extreme environments.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Roisin Owens
Email: rmo37@cam.ac.uk
Department / Partner Institute: Chemical Engineering and Biotechnology
Website: https://www.ceb.cam.ac.uk/research/groups/best/people
Research topic for potential rotation projects: Our group has integrated cell membranes with electronic chips for measuring protein/ pathogen binding and also vesicle fusion. This rotation project would investigate the potential to measure GPCR ligand binding.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Steven Lee
Email: sl591@cam.ac.uk
Department / Partner Institute: Chemistry
Website: https://www.ch.cam.ac.uk/person/sl591
Research topic for potential rotation projects: Development of new biophysical microscopy methods, predominantly through the use of single molecule spectroscopy and super-resolution imaging.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Pietro Sormanni
Email: ps589@cam.ac.uk
Department / Partner Institute: Chemistry
Website: https://www-sormanni.ch.cam.ac.uk
Research topic for potential rotation projects: We combine computational method development and experiments to establish fast and accurate computational technologies to generate novel antibodies for research, diagnostic, and therapeutic applications.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof David Spring
Email: spring@ch.cam.ac.uk
Department / Partner Institute: Chemistry
Website: https://www-spring.ch.cam.ac.uk/index.shtml
Research topic for potential rotation projects: Next generation biotherapeutics and technologies; novel peptide stapling methodologies; photoredox catalysis for bioconjugation; targeted protein degraders.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Samuel Albanie
Email: samuel.albanie.academic@gmail.com
Department / Partner Institute: Engineering
Website: https://samuelalbanie.com/
Research topic for potential rotation projects: Large language modelling (GPT-4 etc.) for accelerated science.
This topic includes: (i) developing tooling, (ii) studying both the opportunities and risks of these models.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Ruchi Choudhary
Email: rc488@cam.ac.uk
Department / Partner Institute: Engineering
Website: http://www.eeci.cam.ac.uk
Research topic for potential rotation projects: Develop Digital Twins to optimize and integrate Vertical Farms with urban infrastructure. As a result, radically reduce the carbon cost of the entire food chain, and reduce energy, land, and water wastes of cities.
BBSRC DTP secondary strategic theme: n/a
Name: Prof John Clarkson
Email: pjc10@eng.cam.ac.uk
Department / Partner Institute: Engineering
Website: https://www-edc.eng.cam.ac.uk/people/pjc10.html
Research topic for potential rotation projects: The application of a systems approach to a bioscience challenge, building on research on the re-design and improvement of complex systems in health and care, policy making and technology.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Matthew Juniper
Email: mpj1001@cam.ac.uk
Department / Partner Institute: Engineering
Website: https://mpj1001.user.srcf.net/MJ_biography.html
Research topic for potential rotation projects: Physics-enhanced Flow-MRI (Magnetic resonance imaging of flows, e.g. those in the body).
Enhance a flow-MRI image to reveal accurate velocity fields, wall positions, wall shear stresses, pressure drops.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Prof Kate Baker
Email: kb827@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.infectiousdisease.cam.ac.uk/staff/kate-baker
Research topic for potential rotation projects: We use microbial genomics to transform our understanding of the epidemiology and biology of bacterial pathogens and antimicrobial resistance.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Tamar Makin
Email: tamar.makin@mrc-cbu.cam.ac.uk
Department / Partner Institute: MRC Cognition and Brain Sciences Unit (CBU)
Website: https://plasticity-lab.com/
Research topic for potential rotation projects: Smart Wearable Biofeedback: Enhancing Yoga Practice & Mindfulness with EMG Tech for Safe, Effective Exercise.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr James Thaventhiran
Email: jedt2@cam.ac.uk
Department / Partner Institute: MRC Toxicology Unit
Website: https://www.mrc-tox.cam.ac.uk/research/thaventhiran-project
Research topic for potential rotation projects: We will investigate how methylpseudouridine (the enabling technology of the Pfizer and Moderna COVID-19 vaccines) regulates T cell antigen expression. Aiming to make mRNA therapies, more effective.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Michael Boemo
Email: mb915@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.boemogroup.org/
Research topic for potential rotation projects: My computational biology laboratory develops artificial intelligence and simulation technologies to study the cell cycle, with a focus on how cells copy and repair their genomes to maintain genome stability.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Mark Howarth
Email: mh2186@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.howarthgroup.org/
Research topic for potential rotation projects: Innovating Protein Technologies for Biotech: protein nanoparticles to activate broadly protective B cells; ultrastable gastrobodies for GI targeting; or protein superglue for non-genetic cell enhancement.
BBSRC DTP secondary strategic theme: Biosciences for an integrated understanding of health
Name: Dr Ioanna Mela
Email: im337@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.ioannamela.com/
Research topic for potential rotation projects: DNA nanotechnology and aptamer selection for targeted drug delivery to procaryotic and eucaryotic targets.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Thorsten Boroviak
Email: teb45@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://boroviaklab.pdn.cam.ac.uk/
Research topic for potential rotation projects: Reconstructing human blastocysts from stem cells to unravel embryo implantation.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Bioscience for an integrated understanding of health
Name: Dr Della David
Email: della.david@babraham.ac.uk
Department / Partner Institute: Babraham Institute
Website: https://www.babraham.ac.uk/our-research/signalling/della-david
Research topic for potential rotation projects: The David lab works on protein aggregation during ageing in C. elegans. We have discovered an extracellular protein quality control program and we are studying how these factors promote healthy ageing.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Eric Miska
Email: eam29@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.ericmiskalab.org/
Research topic for potential rotation projects: The role of non-coding RNA in heart failure; exploration of new biomarkers and therapeutics.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Helen Mott
Email: hrm28@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/mott
Research topic for potential rotation projects: Using biophysical and biochemical approaches to investigate interactions of small G proteins and their effectors with other proteins and/or with membranes.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Martin Welch
Email: mw240@cam.ac.uk
Department / Partner Institute: Biochemistry
Website: https://www.bioc.cam.ac.uk/research/welch
Research topic for potential rotation projects: The team works on the biology of the opportunistic human pathogen, Pseudomonas aeruginosa. We are particularly interested in how biofilms, quorum sensing, and metabolism contribute towards infections.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Janet Deane
Email: jed55@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR)
Website: https://www.cimr.cam.ac.uk/staff/dr-janet-deane
Research topic for potential rotation projects: Identifying new molecular mechanisms driving early-onset neurodegenerative disease. We develop iPSC-based models of rare disease and exploit cutting-edge proteomics to probe how lipid imbalances disrupt cell fate.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Stefan Marciniak
Email: sjm20@cam.ac.uk
Department / Partner Institute: Cambridge Institute for Medical Research (CIMR) / Medicine
Website: https://www.cimr.cam.ac.uk/staff/Prof-stefan-marciniak
Research topic for potential rotation projects: 1. Effects of a1-antitrypsin polymerisation on endoplasmic reticulum biology.
2. Aberrant surfactant trafficking in organoid models of pulmonary fibrosis.
3. Multiomics analysis of mesothelioma organoids.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Gonçalo Bernardes
Email: gb453@cam.ac.uk
Department / Partner Institute: Chemistry
Website: http://www.gbernardeslab.com
Research topic for potential rotation projects: This project will aim to explore proximity-induced nucleic acid degraders (PINADs) to target and degrade cancer-relevant RNA structures. It will include synthesis, biochemistry and cell biology including sequencing.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Melinda Duer
Email: mjd13@cam.ac.uk
Department / Partner Institute: Chemistry
Website: https://www.ch.cam.ac.uk/group/duer/
Research topic for potential rotation projects: Raman imaging and NMR spectroscopy to follow chemistry in extracellular matrix under mechanical tension. Aim is to understand mechanochemistry occurring that may drive cell signaling in ageing.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Michele Vendruscolo
Email: mv245@cam.ac.uk
Department / Partner Institute: Chemistry
Website: http://www-vendruscolo.ch.cam.ac.uk/
Research topic for potential rotation projects: We will be working on small molecule drug discovery to target diseases associated with aberrant protein misfolding, aggregation and condensation, using a combination of experimental and machine learning methods.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Hugh Markus
Email: hsm32@medschl.cam.ac.uk
Department / Partner Institute: Clinical Neurosciences
Website: https://www.cambridgestroke.com/ https://scholar.google.com/citations?user=h-7_PVwAAAAJ&hl=en
Research topic for potential rotation projects: Our work is on cerebral small vessel disease the major cause of vascular dementia. It uses advanced imaging techniques ( MRI) combined with multiomic data to understand the underlying disease mechanims.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Chris Rodgers
Email: ctr28@cam.ac.uk
Department / Partner Institute: Clinical Neurosciences
Website: https://www.neuroscience.cam.ac.uk/directory/profile.php?ctr28
Research topic for potential rotation projects: We develop new methods to study human metabolism in vivo using ultra-high field 7T MRI. The student could help interpret phosphorus MRI data from our study probing the mechanism of SGLT2 inhibitors in heart failure.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Kamen Tsvetanov
Email: kat35@cam.ac.uk
Department / Partner Institute: Clinical Neurosciences
Website: https://www.neuroscience.cam.ac.uk/directory/profile.php?kat35
Research topic for potential rotation projects: The project studies brain resilience in healthy aging using existing neuroimaging, vascular and lifestyle data. Statistical skills (e.g., multivariate) and basic neuroimaging knowledge are helpful but can be taught.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Máté Lengyel
Email: m.lengyel@eng.cam.ac.uk
Department / Partner Institute: Engineering
Website: https://lengyellab.org/
Research topic for potential rotation projects: Computational models of adaptive behaviour and neural circuit dynamics.
BBSRC DTP secondary strategic theme: Understanding the rules of life, Transformative technologies
Name: Dr Charlotte Houldcroft
Email: ch504@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/staff/dr-charlotte-houldcroft
Research topic for potential rotation projects: Nanopore sequencing of adenoviruses with pandemic potential, incl sequencing method development; and characterisation of adaptive anti-adenovirus immunity.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Henrik Salje
Email: hs743@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.pdg.gen.cam.ac.uk/
Research topic for potential rotation projects: The Pathogen Dynamics Group works on the emergence, spread of pathogens, through data driven computational approaches. We have a substantial focus on disease ecology of arboviruses in lower income countries.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Ashraf Zarkan
Email: maa77@cam.ac.uk
Department / Partner Institute: Genetics
Website: https://www.gen.cam.ac.uk/staff/dr-ashraf-zarkan
Research topic for potential rotation projects: Urinary Tract Infections are linked with bacterial biofilms, protecting against the immune system and antibiotics. Cells in the urogenital tract release extracellular vesicles with "potential" antibiofilm activity.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Maria P. Alcolea
Email: mpa28@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/alcolea
Research topic for potential rotation projects: The ability of epithelial cells to rewire their programme of cell fate in response to tissue perturbations has emerged as a new paradigm in stem cell biology. This plasticity improves the efficiency of tissue repair.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Matthias Zilbauer
Email: mz304@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute
Website: https://www.stemcells.cam.ac.uk/people/pi/zilbauer
Research topic for potential rotation projects: Role of epigenetic mechanisms in regulating intestinal epithelial cell function in health and disease using patient derived organoid models.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Joo-Hyeon Lee
Email: jhl62@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute / Physiology, Development and Neuroscience (PDN)
Website: https://www.stemcells.cam.ac.uk/people/pi/lee
Research topic for potential rotation projects: Investigating the role of biomechanical signals on cellular reprogramming and expansion in lung regeneration and cancer development.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Thora Karadottir
Email: rk385@cam.ac.uk
Department / Partner Institute: MRC Cambridge Stem Cell Institute / Veterinary Medicine
Website: https://www.stemcells.cam.ac.uk/people/pi/karadottir
Research topic for potential rotation projects: The focus of our research is to address fundamental mechanisms of myelination, why myelin regeneration fails, and the impact of myelin and failure of myelin regeneration on neuronal circuit function.

BBSRC DTP secondary strategic theme: Transformative technologies

Name: Prof Richard Henson
Email: rik.henson@mrc-cbu.cam.ac.uk
Department / Partner Institute: MRC Cognition and Brain Sciences Unit (CBU)
Website: https://www.mrc-cbu.cam.ac.uk/people/rik.henson/personal/
Research topic for potential rotation projects: Analysing existing genetic, neuroimaging, demographic, lifestyle and cognitive longitudinal data on a sample of healthy adults to understand how ageing affects brain and cognition (www.cam-can.org).
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Amy Orben
Email: amy.orben@mrc-cbu.cam.ac.uk
Department / Partner Institute: MRC Cognition and Brain Sciences Unit (CBU)
Website: https://www.digitalmentalhealth.group
Research topic for potential rotation projects: Social media's impact on habit and attention raises concern. Traditional psycho-biological literature methods, like reward-learning models, are however still underutilized in studying this.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof Susan Ozanne
Email: seo10@cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science - Metabolic Research Laboratories (IMS-MRL)
Website: https://www.mrl.ims.cam.ac.uk/research/principal-investigators/susan-oza...
Research topic for potential rotation projects: Developmental programming of cardio-metabolic health by in utero exposure to an obesogenic environment.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Clemence Blouet
Email: csb69@medschl.cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.blouetlab.org/
Research topic for potential rotation projects: Identifying and characterising the metabolic consequences of dietary protein restriction and the brain mechanisms through which changes in dietary protein intake modulate appetite and metabllism.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Laura Dearden
Email: ld454@medschl.cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.mrl.ims.cam.ac.uk/about-us/our-people/early-career-investiga...
Research topic for potential rotation projects: Our research focuses on how obesity during pregnancy alters development of a part of the baby's brain called the hypothalamus, and leads to an increased obesity risk in offspring later in life.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Florian Merkle
Email: fm436@medschl.cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.merklelab.org/
Research topic for potential rotation projects: Our group generates human hypothalamic cell populations that regulate essential processes, such as eating or reproduction. You will learn cutting-edge techniques as you study these cells in health and disease.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Zahid Padamsey
Email: zp278@cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.mrl.ims.cam.ac.uk/research/principal-investigators/zahid-pad...
Research topic for potential rotation projects: How metabolic hormones regulate brain function and energy use is poorly understood. This project will examine how metabolic hormones affect neuronal metabolism and function in vitro using calcium and oxygen imaging.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Frank Reimann
Email: fr222@medschl.cam.ac.uk
Department / Partner Institute: MRC Institute of Metabolic Science (IMS) / Clinical Biochemistry
Website: https://www.mrl.ims.cam.ac.uk/research/principal-investigators/frank-rei...
Research topic for potential rotation projects: Control of food intake along the gut-brain axis - live cell imaging of enteroendocrine cells in intestinal organoids or target neurons in acute brain slices (cAMP/Ca2+responses).
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Patrick Chinnery
Email: pfc25@cam.ac.uk
Department / Partner Institute: MRC Mitochondrial Biology Unit (MBU) / Clinical Neurosciences
Website: https://www.mrc-mbu.cam.ac.uk/research-groups/chinnery-group
Research topic for potential rotation projects: High-throughput single-cell multi-omics to understand how the cell nucleus communicates with mitochondria in health and disease.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Anne Willis
Email: aew80@cam.ac.uk
Department / Partner Institute: MRC Toxicology Unit
Website: https://www.mrc-tox.cam.ac.uk/staff/anne-willis-obe
Research topic for potential rotation projects: Control of mRNA translation and in particular reprogramming of the translatome and synthesis of specific proteins required for stress protection/apoptosis with a focus on regulation of elongation.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Ritwick Sawarkar
Email: rs2099@cam.ac.uk
Department / Partner Institute: MRC Toxicology Unit / Genetics
Website: https://www.gen.cam.ac.uk/research-groups/research-groups/sawarkar-group
Research topic for potential rotation projects: Systems biology and CRISPR screening approaches to understand the regulation of tRNA genes in different cell-types and in response to stress: novel mechanisms linking signaling and epigenome to DNA sequences.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Andrew Blagborough
Email: amb283@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/andrew-blagborough
Research topic for potential rotation projects: This project aims to build a molecular map of the poorly understood process of fertilisation in the Plasmodium parasite that causes malaria to aid the eventual development of a novel anti-malarial vaccine.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Louise Boyle
Email: lhb22@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.teamtapbpr.co.uk/
Research topic for potential rotation projects: We focus on MHC molecules which play a key role in inducing protective immune responses against tumours and pathogens. Our work has significant translational potential in infectious disease, cancer and autoimmunity.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Colin Crump
Email: cmc56@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/research/virology-division/crump-group
Research topic for potential rotation projects: Discovering and investigating virus-host interactions required to remodel infected cells and evade antiviral responses.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Anton Enright
Email: aje39@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/anton-enright
Research topic for potential rotation projects: Using nanopore sequencing to detect and quantify RNAs and RNA modifications with important roles in diseases such as cancer.
This would be a combined wet/dry project with both lab and computation skills developed.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Brian Ferguson
Email: bf234@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/research/immunology-division/ferguson-group
Research topic for potential rotation projects: Discovery of novel components of mammalian and avian antiviral pattern recognition receptor signalling using comparative immunology.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Ian Goodfellow
Email: ig299@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.path.cam.ac.uk/directory/ian-goodfellow
Research topic for potential rotation projects: Understanding the role of the core stress granule component, G3BP-1, in the novel paradigm of Norovirus VPg-dependent translation initiation.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Anna Protasio
Email: avp25@cam.ac.uk
Department / Partner Institute: Pathology
Website: https://www.annaprotasio-lab.com/
Research topic for potential rotation projects: We investigate zoonotic pathogens in wild birds, we are interested in early detection and co-infections, how these after ecology & conservation projects and potential spillovers into farm animals and humans.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Matthew Harper
Email: mth29@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/harper
Research topic for potential rotation projects: Platelets and coagulation are essential parts of the haemostatic system that prevents bleeding. Our lab studies how platelets and coagulation interact and looks for new anti-platelet targets to prevent thrombosis.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Graham Ladds
Email: grl30@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/Ladds
Research topic for potential rotation projects: G protein-coupled receptors (GPCRs) remain the leading target for therapeutic intervention. Using bioluminescent techniques we study, how drugs bring about GPCR activation and generate off target signalling events.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Maria Marti-Solano
Email: mm2402@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/marti
Research topic for potential rotation projects: We use computational biology and bioinformatics methods to integrate structural, multi-omics, network biology, cell signalling, and pharmacogenomics data to explore receptor signalling in health and disease.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Hendrik van Veen
Email: hwv20@cam.ac.uk
Department / Partner Institute: Pharmacology
Website: https://www.phar.cam.ac.uk/research/vanveen
Research topic for potential rotation projects: Please join our research on antibiotic efflux pumps that remove antibiotics from bacterial pathogens. Let's work together to find new therapeutic solutions to inhibit these pumps and eradicate antibiotic resistance.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Walid Khaled
Email: wtk22@cam.ac.uk
Department / Partner Institute: Pharmacology / MRC Cambridge Stem Cell Institute
Website: www.wtklab.com
Research topic for potential rotation projects: Our lab is interested in identifying early cellular changes that precede breast tumour development using single cell genomics. This project will investigate the role of Yap/Taz in these precancerous changes.
BBSRC DTP secondary strategic theme: Understanding the rules of life, Transformative technologies
Name: Prof Dino Giussani
Email: dag26@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/dino-giussani
Research topic for potential rotation projects: Current focus: Does maternal obesity trigger embryonic origins of heart disease? We use animal models (PMID: 35534925; 36724801; 37132324) and offer expertise with in vivo and isolated organ cardiovascular function.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof David Keays
Email: dak55@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: http://www.keayslab.org
Research topic for potential rotation projects: Modelling Human Neurodevelopmental Disease with Cerebral Organoids.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Andrew Murray
Email: ajm267@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/andrew-murray
Research topic for potential rotation projects: Oxygen sensing and integrated mitochondrial physiology in metabolic disease. Our work seeks to understand how mitochondrial respiratory function is altered in tissues downstream of compromised oxygen supply.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Angela Roberts
Email: acr4@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/angela-roberts
Research topic for potential rotation projects: The lab is interested in the neural circuits underlying emotion regulation in both the positive and negative domains. In particular, the role of the prefrontal cortex and the interactions within its subregions.
BBSRC DTP secondary strategic theme: n/a
Name: Prof Amanda Sferruzzi-Perri
Email: ans48@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN)
Website: https://www.pdn.cam.ac.uk/directory/amanda-sferruzzi-perri
Research topic for potential rotation projects: Identifying the mechanisms by which placental malfunction or a suboptimal parental environment impacts fetal development and health.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Emma Rawlins
Email: elr21@cam.ac.uk
Department / Partner Institute: Physiology, Development and Neuroscience (PDN) / Gurdon Institute
Website: https://www.gurdon.cam.ac.uk/people/emma-rawlins/
Research topic for potential rotation projects: We use human lung organoid models, CRISPR tools and imaging and single cell approaches to answer fundamental questions about cell fate decisions and coordinated morphogenesis to understand human lung development.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Paul Bays
Email: pmb20@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://bayslab.org
Research topic for potential rotation projects: Using Distorted Reality experiments (online manipulation of live binocular camera feed displayed in a VR headset) to investigate how the human visual system is adapted to statistics of the natural environment.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Prof David Belin
Email: bdb26@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.psychol.cam.ac.uk/staff/Prof-david-belin
Research topic for potential rotation projects: Humans and other animals are not equally able to recognise their internal states. This alexithymia hampers adaptive emotion regulation and coping strategies. This project aims to uncover its neural basis.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Richard Bethlehem
Email: rb643@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.neuroscience.cam.ac.uk/directory/profile.php?rb643
Research topic for potential rotation projects: Lifespan neuroinformatics: studying brain health across the lifespan using neuroimaging, genetics and machine learning on big population data collaborating with computer science, psychiatry and clinical neuroscience.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Sarah-Jayne Blakemore
Email: sjblakemore@psychol.cam.ac.uk
Department / Partner Institute: Psychology
Website: https://sites.google.com/site/blakemorelab/
Research topic for potential rotation projects: This project will investigate the influence of social rewards and threats on learning in late adolescence.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Prof Nicola Clayton
Email: nsc22@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://www.psychol.cam.ac.uk/people/nsc22%40cam.ac.uk
Research topic for potential rotation projects: Comparative cognition amongst corvids and humans. Cephalopod cognition. Corvid cognition. Mental time travel, memory and future decision making. Theory of mind. Tool use and problem solving. Story telling. Caching.

BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food

Name: Prof Jon Simons
Email: jss30@cam.ac.uk
Department / Partner Institute: Psychology
Website: http://www.memlab.psychol.cam.ac.uk
Research topic for potential rotation projects: Our research focuses on the cognitive and brain mechanisms of human memory, and how they change across the lifecourse. By understanding these processes, we aim to develop methods to enhance remembering in older age.
BBSRC DTP secondary strategic theme: n/a
Name: Dr Deborah Talmi
Email: dt492@cam.ac.uk
Department / Partner Institute: Psychology
Website: https://dtalmi.wixsite.com/website/meet-the-team
Research topic for potential rotation projects: Effect of emotion on memory encoding and probabilistic learning: A critical test of the dual-representation account of post-traumatic stress disorder.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Carl Anderson
Email: carl.anderson@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: http://andersonlab.info/
Research topic for potential rotation projects: Large-scale single-cell RNA sequencing study of hundreds of healthy gut biopsies to understand, at cell type resolution, how gene expression varies by intestinal site, age and sex.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Josie Bryant
Email: jb31@sanger.ac.uk
Department / Partner Institute: Sanger Institute
Website: https://www.sanger.ac.uk/external_person/bryant-josie/
Research topic for potential rotation projects: Our aim is to understand the role of the respiratory microbiome in chronic lung disease. We are developing high-throughput methods to generate and analyse deep metagenomic data from patient samples.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Sarah Teichmann
Email: sat1003@cam.ac.uk
Department / Partner Institute: Sanger Institute
Website: https://www.sanger.ac.uk/group/teichmann-group/
Research topic for potential rotation projects: We use cutting-edge single-cell and spatial gene expression approaches, combined with human genetics at the cellular level to build a Human Cell Atlas, with a particular focus on studying the immune system.
BBSRC DTP secondary strategic theme: Transformative technologies
Name: Dr Alexandre Almeida
Email: aa2369@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.vet.cam.ac.uk/staff/dr-alexandre-almeida
Research topic for potential rotation projects: Application of large-scale metagenomic methods to explore the role of the human gut microbiome in human health. The project will involve a combination of microbiology, bioinformatics and genomics techniques.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Kate Hughes
Email: kh387@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.vet.cam.ac.uk/directory/hughes
Research topic for potential rotation projects: My group studies the mammary gland microenvironment in non-traditional model species particularly ruminants and rabbits. Project would use deep 3-dimensional tissue clearing and imaging to localise immune cells.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Prof Elizabeth Murchison
Email: epm27@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.tcg.vet.cam.ac.uk/
Research topic for potential rotation projects: Genetic analysis of transmissible cancers in dogs and Tasmanian devils. Transmissible cancers occur when cancer cells themselves become infectious agents and spread through populations.
BBSRC DTP secondary strategic theme: Understanding the rules of life
Name: Dr Lucy Weinert
Email: lw461@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.infectiousdisease.cam.ac.uk/directory/lw461%40cam.ac.uk
Research topic for potential rotation projects: My research investigates the genomics and evolution of bacterial pathogenicity, with a focus on zoonoses and antimicrobial resistance.
BBSRC DTP secondary strategic theme: Bioscience for sustainable agriculture and food
Name: Dr Tim Williams
Email: tlw27@cam.ac.uk
Department / Partner Institute: Veterinary Medicine
Website: https://www.vet.cam.ac.uk/directory/tlw27
Research topic for potential rotation projects: Investigating the mechanism of antimicrobial activity of urinary extracellular vesicles (EVs). This project will utilise super resolution confocal microscopy to study the interaction between EVs and bacteria.
BBSRC DTP secondary strategic theme: Understanding the rules of life