iCase projects for academic year 2023-2024
This list may continued to be updated, and additional projects added until the end of October 2022.
An organoid platform for defining molecular effectors of colorectal cancer malignancy Dr Marc de la Roche (Biochemistry) |
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Antibody-drug conjugates for targeted treatment of cellular senescence in lung cancer and respiratory disease Dr Ljiljana Fruk (Chemical Engineering and Biotechnology) |
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Characterisation of new cellular pathways reversing cellular ageing Dr Delphine Larrieu (Pharmacology) |
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Deciphering the molecular basis of amylin receptor-mediated satiation as an obesity treatment Prof Graham Ladds (Pharmacology) |
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Developing an ethological system for studying spatial working memory in mice Dr Julija Krupic (Physiology, Development and Neuroscience) |
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Developing an organ-on-a-chip platform for identifying potent AAV with improved cell targeting for delivery of gene therapy Prof Róisín M. Owens (Chemical Engineering and Biotechnology) |
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Elucidating the mechanisms AAV employs to evade host cell immune responses Dr Colin Crump (Pathology) |
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Engineering the internal and external environment of leafy crops to enhance indoor growth and provide food for space exploration Prof Alex Webb (Plant Sciences) |
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Genetic improvement of the Black Soldier Fly Prof Chris Jiggins (Zoology) |
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How do soluble enzymes from microbes degrade insoluble plant cell walls? Prof Paul Dupree (Biochemistry) |
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Identifying and quantifying new peptide biomarkers of intestinal and metabolic disease using mass spectrometry Dr Richard Kay (Wellcome - MRC Institute of Metabolic Science) |
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Identifying the SARM1-dependent enzyme activity that drives axon death Prof Michael Coleman (Clinical Neurosciences) |
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Machine learning to understand the radiogenomics of resistance in ovarian cancer Dr Mireia Crispin (Oncology) |
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Neuroimmune regulation of gut function Dr David Bulmer (Pharmacology) |
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Optimising diversity capture and maximising genetic gain within pre-breeding wheat programs Dr Tally Wright (NIAB) |
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Optimization and characterization of functionally active anti-Cdc42/Ras peptides Dr Darerca Owen (Biochemistry) |
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Phase transitions underlying viral replication: the role of biomolecular condensates in segmented RNA viral genome assembly Dr Alex Borodavka (Biochemistry) |
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Scaling-up biodiversity reporting in food supply chains: developing a global farm-scale biodiversity metric for sustainable agriculture Dr Lynn Dicks (Zoology) |
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Stemness and maintenance of CD4+ regulatory T cell (Treg) responses in homeostasis, inflammation and ageing Dr Rahul Roychoudhuri (Pathology) |
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Study of the human hypothalamic circuitry regulating appetite Prof Giles Yeo (Wellcome - MRC Institute of Metabolic Science) |
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The role of GABAa and GABAb receptors in visual learning and decision-making Prof Jeff Dalley (Psychology) |
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Understanding and manipulating rAAV DNA biology Prof Kathryn Lilley (Biochemistry) |
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Understanding the regulation of flowering in the herbaceous plant Coriandrum sativum L. Dr Matthew Milner (NIAB) |