iCase projects for academic year 2023-2024
This list may continued to be updated, and additional projects added until the end of October 2022.
| An organoid platform for defining molecular effectors of colorectal cancer malignancy Dr Marc de la Roche (Biochemistry) |
|
| Antibody-drug conjugates for targeted treatment of cellular senescence in lung cancer and respiratory disease Dr Ljiljana Fruk (Chemical Engineering and Biotechnology) |
|
| Characterisation of new cellular pathways reversing cellular ageing Dr Delphine Larrieu (Pharmacology) |
|
| Deciphering the molecular basis of amylin receptor-mediated satiation as an obesity treatment Prof Graham Ladds (Pharmacology) |
|
| Developing an ethological system for studying spatial working memory in mice Dr Julija Krupic (Physiology, Development and Neuroscience) |
|
| Developing an organ-on-a-chip platform for identifying potent AAV with improved cell targeting for delivery of gene therapy Prof Róisín M. Owens (Chemical Engineering and Biotechnology) |
|
| Elucidating the mechanisms AAV employs to evade host cell immune responses Dr Colin Crump (Pathology) |
|
| Engineering the internal and external environment of leafy crops to enhance indoor growth and provide food for space exploration Prof Alex Webb (Plant Sciences) |
|
| Genetic improvement of the Black Soldier Fly Prof Chris Jiggins (Zoology) |
|
| How do soluble enzymes from microbes degrade insoluble plant cell walls? Prof Paul Dupree (Biochemistry) |
|
| Identifying and quantifying new peptide biomarkers of intestinal and metabolic disease using mass spectrometry Dr Richard Kay (Wellcome - MRC Institute of Metabolic Science) |
|
| Identifying the SARM1-dependent enzyme activity that drives axon death Prof Michael Coleman (Clinical Neurosciences) |
|
| Machine learning to understand the radiogenomics of resistance in ovarian cancer Dr Mireia Crispin (Oncology) |
|
| Neuroimmune regulation of gut function Dr David Bulmer (Pharmacology) |
|
| Optimising diversity capture and maximising genetic gain within pre-breeding wheat programs Dr Tally Wright (NIAB) |
|
| Optimization and characterization of functionally active anti-Cdc42/Ras peptides Dr Darerca Owen (Biochemistry) |
|
| Phase transitions underlying viral replication: the role of biomolecular condensates in segmented RNA viral genome assembly Dr Alex Borodavka (Biochemistry) |
|
| Scaling-up biodiversity reporting in food supply chains: developing a global farm-scale biodiversity metric for sustainable agriculture Dr Lynn Dicks (Zoology) |
|
| Stemness and maintenance of CD4+ regulatory T cell (Treg) responses in homeostasis, inflammation and ageing Dr Rahul Roychoudhuri (Pathology) |
|
| Study of the human hypothalamic circuitry regulating appetite Prof Giles Yeo (Wellcome - MRC Institute of Metabolic Science) |
|
| The role of GABAa and GABAb receptors in visual learning and decision-making Prof Jeff Dalley (Psychology) |
|
| Understanding and manipulating rAAV DNA biology Prof Kathryn Lilley (Biochemistry) |
|
| Understanding the regulation of flowering in the herbaceous plant Coriandrum sativum L. Dr Matthew Milner (NIAB) |
