These are examples of rotation and PhD projects undertaken by students on the Cambridge Biosciences BBSRC DTP.
We want to ensure that every student has the right projects for them. To help student identify projects that are within theme and suitable for BBSRC DTP funding each year we collate a new list of projects (c.200) from across the different departments and partner institutes for students to select from. This however is not an exhasutive list and students are also welcome to arrange their own rotation/ PhD projects that will then be approved by the Research Committee. Only once funding from the programme has been guaranteed should students start to arrange their projects.
Projects took place pre 2019 but have been mapped to the new BBSRC themes that were introduced for 2020.
Standard/ Targeted studentships
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PhDHuman behaviour, the flow of information and the spread and control of crop disease. (Plant Sciences)
Rotation 1 Investigating the role of genetic interactions in the control of agronomic traits in wheat. (NIAB) Rotation 2 Using citrus as a model for scaling control of disease at local scales to strategies for regional control. (Plant Sciences) Themes Biosciences for sustainable agriculture and food |
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PhD Pathophysiological role of lysophosphatidylacyltransferases (LPLATs) on adipose tissue expansion and Metabolic Syndrome.(Clinical Biochemistry -Institute of Metabolic Science)
Rotation 1 LPLATs in phospholipid remodelling and its role on adipose tissue expansion and associated metabolic complications (Clinical Biochemistry -Institute of Metabolic Science) Rotation 2 Dissecting nuclear dynamics in migrating leukocytes during immune responses (PDN) Themes Understanding the rules of life and Bioscience for an integrated understanding of health |
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PhD Developmental Lineage Tracing of Self-Renewing Alveolar Progenitors in the Mouse Lung using an Unbiased Approach (Pathology/ Gurdon Institute)
Rotation 1 Developing Mini-Brains from Well-Defined Synthetic Matrices (Chemistry) Rotation 2 Resolving single cell states in human embryonic lungs (Pathology/ Gurdon Institute) Themes Understanding the rules of life and Bioscience for an integrated understanding of health |
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PhD Exploring Novel Deep Learning Methods for Drug Discovery and Protein Structure Prediction (Biochemistry and Computer science and Technology)
Rotation 1 A Multi-modal Variational autoencoder approach to mycobacterium tuberculosis data integration (Computer science and Technology) Rotation 2 Systems Understanding and Choke-Point Analysisof Mycobacterium tuberculosis drug targets (Biochemistry) Themes Transformative technologies and Bioscience for an integrated understanding of health |
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PhD Engineering Patrolling Microbes for Controlled Pulsatile Delivery of Antimicrobial Agents in Microbial Communities (Engineering/ Plant Sciences)
Rotation 1 Investigating Cell-Free Systems as Synthetic Biology Tools for Biomanufacturing (Plant Sciences) Rotation 2 Yeast Mutator - In-vivo Directed Evolution in Saccharomyces cerevisiae (Pathology) Themes Transformative technologies and Bioscience for renewable resources and clean growth |
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PhD Exploring RAC-GEF independent roles of PREX1 in neutrophils (Babraham Institute)
Rotation 1 Tiam-1 dependent neutrophil adhesion (Babraham Institute) Rotation 2 Establish conditions of neutrophil preparation and stimulation that will yield reproducible measurements of PIP3, using the LSPH lab’s unique mass spectrometry method. (Babraham Institute) Themes Understanding the rules of life and Transformative technologies |
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PhD The Impact of Management to Restore River Margins in Tropical Agricultural Landscapes on Ant Communities (Zoology)
Rotation 1 Experimental study of wear in smooth adhesive pads of insects (Zoology) Rotation 2 The impact of relaxed management on subterranean fauna (Zoology) Themes Biosciences for sustainable agriculture and food |
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PhD Modelling mechanosensitivity of the 2nd kind: how cells feel and respond to stiffness of their environment (Physics)
Rotation 1 Consolidation of focal adhesions and transition to cell motility (Physics) Rotation 2 How mechanical cues affect plant cell morphology and behaviour (Physics) Themes Understanding the rules of life |
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PhD Novel antibiotics that target essential membrane transporters in pathogenic bacteria (Pharmacology)
Rotation 1 (Pharmacology) Rotation 2 Peptide synthesis towards inhibiting essential membrane transporters in pathogenic bacteria (Chemistry) Themes Bioscience for an integrated understanding of health |
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PhD Investigating the role of KRAB-ZFPs in the establishment of species-specific GRNs (Genetics)
Rotation 1 Generate cellular models for candidate KRAB-ZFPs (Genetics) Rotation 2 Chromatin-mediated regulation of alternative splicing (Genetics) Themes Understanding the rules of life |
Case studentships
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PhD A Novel Lipidomic Tool for Monitoring ER-stress and its role in diet induced cellular dysfunction.
Department/ Industrial Partner Biochemistry/ Unilever Theme Understanding the rules of life |
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PhD Using Transcriptomics Data to Understand Drug Mode-of-Action
Department/Industrial Partner Chemistry/Eli Lilly and Company Theme Bioscience for an integrated understanding of health |
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PhD Domestication of the Black Soldier Fly
Department/Industrial Partner Zoology/Entomics Theme Transformative techologies |
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PhD Identification of genetic regulators of photosynthetic carbon storage in wheat
Department/ Industrial Partner Plant Sciences/Bayer CropScience Theme Bioscience for sustainable agriculture and food |
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PhD Investigation of livestock associated MRSA (ST398) in the UK pig herd
Department/ Industrial Partner Veterinary Medicine/DaleHead Foods Theme Bioscience for sustainable agriculture and food |
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PhD Mass spectrometric analysis of plasma peptides involved in metabolic responses to gastric bypass surgery and nutrition
Department/Industrial Partner Institute of Metabolic Science/LGC Drug Development Services Theme Bioscience for an integrated understanding of health |
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PhD Decoding the network logic governing resetting of pluripotency
Department/Industrial Partner Biochemistry & Stem Cell Institute/Microscoft Research Ltd. Theme Understanding the rules of life |