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Cambridge Biosciences DTP PhD Programme


Department of Pharmacology

Research theme: Bioscience for an integrated understanding of health


Prior to my PhD I completed my undergraduate course at Cambridge. I then took a year out of academia, enabling me to travel and visit friends and family across the globe. During this time I worked as a tailor, a new skill which I have since employed! Aside from my PhD, I am an avid painter and sketcher, focusing on painting my and my families pets. I am also a competitive archer, shooting a compound bow for 2 years, after shooting a recurve bow for 8 years previously.


Project Title:

Unravelling the mechanisms of GLP1R internalisation

Project Summary:

I am looking at internalisation and signalling of the glucagon-like peptide-1 receptor (GLP1R). In particular, I am focused on interactions with receptor activity modifying proteins (RAMPs), and now these influence GLP1R signalling. I am then investigating how these changes in signalling and internalisation affect the potentiation of insulin secretion by GLP1


Key publications: 

Combinatorial expression of GPCR isoforms affects signalling and drug responses. Nature, 2020,
Novel mathematical and computational models of G protein–coupled receptor signalling,Current Opinion in Endocrine and Metabolic Research, 2021,

Teaching and Supervisions

Research supervision: 

Dr Graham Ladds

Staff Photo

Contact Details

Job Titles

PhD Student