Babraham Institute
Research theme: Understanding the rules of life
Biography
I graduated from the University of Birmingham in 2021 with an Integrated Masters degree in Biochemistry. I spent my third of four years on placement on the Cellular and Molecular Biology team at biotechnology company Storm Therapeutics (based at Babraham Research Campus in Cambridge), a company looking to create inhibitors for RNA-modifying enzymes to be used as a novel cancer treatment. Through this experience, I developed an interest in the roles played by RNA other than directly in protein expression. My final year project, too, had an RNA theme, looking at how RNA helicases and how they affect RNA structure. I have now returned to Cambridge to begin my PhD at the Babraham Institute, with my current research incorporating my previous experiences, looking at RNA structure in relation to B cell development and diseases.
Alongside my interest in RNA biology, in my free time I enjoy hiking and camping with friends, and also textile art, in particular embroidery and crochet.
Research
Project Title:
Exploring the role of RNA structures in B-cell development and disease
Project Summary:
B cells develop into antibody-secreting cells through a mechanism of DNA recombination and mutation of antibody genes. It has recently been found that RNA and RNA-binding proteins play a key role in this process. However, current knowledge of how antibody gene rearrangement is regulated at the RNA level is minimal.
Teaching and Supervisions
Dr Claudia Ribeiro de Almeida